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Cruises from Istanbul to Rome

Are you looking for a cruise from Istanbul to Rome? October is the most popular month to cruise between Istanbul and Rome and there are 42 departures available from seven of the world's leading cruise lines.
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8 Days
22 Days
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$1,900pp
$39,095pp
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15 Cruises (42 Cruise Departures)
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departures: May 2026 to Sep 2026
Countries Visited: Turkey, Greece, Malta, Sicily (+1 more), Italy
NCL's More at Sea
INSIDE
$4,520
OCEANVIEW
$5,055
BALCONY
$6,049
SUITE
$7,181
From (per person) 4,520
View Trip
15 Day Ancient Mediterranean Antiquities with Viking Cruises
Cruise
 (6)

15 Days (14 Nights) Istanbul to Rome
Operated By: Viking Cruises
Ships: Viking Mira, Viking Neptune (+5 more), Viking Saturn, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Oct 2025 to Jan 2027
Countries Visited: Turkey, Greece, Sicily, Italy
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$10,775
SUITE
$15,675
Save (per person) 408
From (per person) 10,775
View Trip
11 Day Greece & Italy with Princess
Cruise
 (2)

11 Days (10 Nights) Istanbul to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 19 July 2025
Countries Visited: Turkey, Greece, Montenegro, Sicily (+1 more), Italy
Exclusive Deal
INSIDE
$2,205
OCEANVIEW
$2,621
BALCONY
$2,997
SUITE
$3,413
From (per person) 2,205
View Trip
22 Day Adriatic & Mediterranean Sojourn with Viking Cruises
Cruise
 (5)

22 Days (21 Nights) Istanbul to Rome
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+6 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vesta
Departures: Jun 2025 to Jul 2027
Countries Visited: Turkey, Greece, Montenegro, Croatia (+2 more), Sicily, Italy
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$19,301
SUITE
$28,611
Save (per person) 782
From (per person) 19,301
View Trip
21 Day Revered & Romantic Shores with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 12 November 2026
Countries Visited: Turkey, Greece, Montenegro, Croatia (+4 more), Italy, Slovenia, Malta, Sicily
Exclusive Deal
INSIDE
$8,456
OCEANVIEW
$9,208
BALCONY
$13,861
SUITE
$19,583
Save (per person) 2,054
From (per person) 8,456
View Trip
22 Day Istanbul, Greek Isles And Adriatic with Cunard
Cruise

22 Days (21 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 19 May 2025
Countries Visited: Turkey, Greece, Italy, Montenegro (+2 more), Croatia, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$5,768
BALCONY
-
SUITE
-
From (per person) 5,768
View Trip
17 Day Jewels Of The Adriatic & Aegean with Seabourn
Cruise

17 Days (16 Nights) Istanbul to Rome
Cruise Line: Seabourn
Ship: Seabourn Encore
Departure: 26 October 2025
Countries Visited: Turkey, Greece, Montenegro, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,591
SUITE
$23,976
From (per person) 12,591
View Trip
13 Day Mythical Places, Magical Nights with Regent Seven Seas
Cruise

13 Days (12 Nights) Istanbul to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 13 May 2025
Countries Visited: Turkey, Greece, Croatia, Malta (+1 more), Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$36,152
From (per person) 36,152
View Trip
12 Day Greek Isles & Eastern Med with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sky
Departure: 14 June 2025
Countries Visited: Turkey, Greece, Sicily, Italy (+1 more), France
NCL's More at SeaExclusive Solo Offer
INSIDE
$3,089
OCEANVIEW
$3,547
BALCONY
$5,383
SUITE
$7,613
From (per person) 3,089
View Trip
13 Day Knights & Emperors with Regent Seven Seas
Cruise

13 Days (12 Nights) Istanbul to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 28 June 2026
Countries Visited: Turkey, Greece, Croatia, Montenegro (+2 more), Italy, Malta
Upgrade Your HorizonExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,392
SUITE
$16,124
Save (per person) 6,338
From (per person) 15,392
View Trip
15 Day Turkey, Greece & Roman Gems with Seabourn
Cruise

15 Days (14 Nights) Istanbul to Rome
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 18 October 2026
Countries Visited: Turkey, Greece, Albania, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$12,689
BALCONY
$15,263
SUITE
$30,509
From (per person) 12,689
View Trip
13 Day Greek Isles & Eastern Med with Norwegian Cruise Line
Cruise

13 Days (12 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sky
Departure: 02 October 2025
Countries Visited: Turkey, Greece, Malta, Sicily (+2 more), Italy, France
NCL's More at Sea
INSIDE
$4,138
OCEANVIEW
$4,750
BALCONY
$7,427
SUITE
$12,755
From (per person) 4,138
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Countries Visited: Turkey, Greece, Italy
Exclusive Deal
INSIDE
$1,981
OCEANVIEW
$2,130
BALCONY
$2,526
SUITE
$5,199
From (per person) 1,981
View Trip
22 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

22 Days (21 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 11 May 2026
Countries Visited: Turkey, Greece, Spain, France (+3 more), Italy, Corsica, Sicily
Exclusive Deal
INSIDE
$5,253
OCEANVIEW
$5,946
BALCONY
$6,778
SUITE
$13,866
From (per person) 5,253
View Trip
8 Day Istanbul And Greek Isles with Cunard
Cruise

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 19 May 2025
Countries Visited: Turkey, Greece, Italy
Exclusive Deal
INSIDE
$1,932
OCEANVIEW
-
BALCONY
$2,912
SUITE
$4,506
From (per person) 1,932
View Trip
Results: 15 results

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