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Cruises Starting and Ending in Santos

Are you looking for a cruise starting and ending in Santos? December is the most popular month to join a roundtrip cruise from Santos and we have 40 departures available from one of the world's leading cruise lines.
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4 Days
9 Days
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$400pp
$5,225pp
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16 Cruises (40 Cruise Departures)
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 26 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$2,612
OCEANVIEW
$2,889
BALCONY
$3,315
SUITE
$3,988
From (per person) 2,612
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Feb 2025 to Mar 2025
Countries Visited: Brazil, Argentina, Uruguay
Early Booking Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$2,074
SUITE
$2,757
From (per person) 2,074
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 23 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
-
OCEANVIEW
$1,566
BALCONY
$1,665
SUITE
$2,397
From (per person) 1,566
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 13 March 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$816
OCEANVIEW
-
BALCONY
-
SUITE
$1,538
From (per person) 816
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 13 February 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,470
OCEANVIEW
-
BALCONY
-
SUITE
$2,698
From (per person) 1,470
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 17 January 2026
Countries Visited: Brazil, Argentina, Uruguay
Early Booking Offer
INSIDE
$1,444
OCEANVIEW
-
BALCONY
$2,117
SUITE
$2,919
From (per person) 1,444
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departures: Dec 2025 to Jan 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,282
OCEANVIEW
-
BALCONY
-
SUITE
$2,450
From (per person) 1,282
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 22 February 2026
Countries Visited: Brazil, Argentina, Uruguay
Early Booking Offer
INSIDE
$1,282
OCEANVIEW
$1,520
BALCONY
$1,698
SUITE
$2,569
From (per person) 1,282
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 06 February 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$816
OCEANVIEW
-
BALCONY
-
SUITE
$1,538
From (per person) 816
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Lirica
Departures: Mar 2025 to Jan 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$687
OCEANVIEW
$1,212
BALCONY
-
SUITE
$1,410
From (per person) 687
View Trip
6 Day South America with MSC Cruises
Cruise

6 Days (5 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 27 February 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
-
OCEANVIEW
$1,482
BALCONY
-
SUITE
-
From (per person) 1,482
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Jan 2026 to Mar 2026
Countries Visited: Brazil, Uruguay, Argentina
Early Booking Offer
INSIDE
$1,223
OCEANVIEW
$1,430
BALCONY
$1,619
SUITE
$2,490
From (per person) 1,223
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Preziosa
Departures: Jan 2026 to Mar 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$766
OCEANVIEW
$895
BALCONY
$994
SUITE
$1,529
From (per person) 766
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Dec 2025 to Dec 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$476
OCEANVIEW
$624
BALCONY
$674
SUITE
$1,119
From (per person) 476
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Nov 2025 to Dec 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$796
OCEANVIEW
$915
BALCONY
$1,014
SUITE
$1,538
From (per person) 796
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 29 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,975
OCEANVIEW
-
BALCONY
-
SUITE
$3,212
From (per person) 1,975
View Trip
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