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Main River Luxury River Cruises

Explore the best luxury river cruises along the Main river. Choose from 17 unique river cruise itineraries with 123 past traveller reviews from 1 leading river cruise lines. July and September are the most popular months to join a luxury river cruise along the Main river with 116 departures starting between April 2025 and December 2025.
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17 River Cruises (116 River Cruise Departures)
8 Day Highlights of the Rhine and Main with APT
River Cruise

8 Days Amsterdam to Munich
Operated By: APT
Ships: APT Ostara, APT Solara (+2 more), MS AmaStella, MS AmaVenita
Departures: Jun 2024 to Nov 2025
Rivers: Rhine, Main
Countries Visited: Holland, Germany
Exclusive Deal
Save 1,935
From 4,359
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15 Day Magnificent Europe with APT
River Cruise
 (59)

15 Days Amsterdam to Budapest
Operated By: APT
Ships: APT Ostara, APT Solara (+3 more), MS AmaReina, MS AmaStella, MS AmaVenita
Departures: Jun 2024 to Dec 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+1 more), Hungary
Flights IncludedLast Minute Deals
Save 1,785
From 8,425
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15 Day Magnificent Europe with APT
River Cruise
 (30)

15 Days Budapest to Amsterdam
Operated By: APT
Ships: APT Ostara, APT Solara (+3 more), MS AmaReina, MS AmaStella, MS AmaVenita
Departures: Jul 2024 to Dec 2025
Rivers: Danube, Main, Rhine
Countries Visited: Hungary, Slovakia, Austria, Germany (+1 more), Holland
Flights IncludedLast Minute Deals
Save 1,785
From 8,425
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21 Day Magnificent Europe - Prague to Paris with APT
River Cruise
 (7)

21 Days Prague to Paris
Operated By: APT
Ships: APT Ostara, APT Solara (+2 more), MS AmaStella, MS AmaVenita
Departures: Aug 2024 to Dec 2025
Rivers: Danube, Main, Rhine
Countries Visited: Czech Republic, Hungary, Austria, Slovakia (+4 more), Germany, Holland, Belgium, France
Flights Included
Save 669
From 13,872
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18 Day Magnificent Europe with Prague with APT
River Cruise
 (10)

18 Days Amsterdam to Prague
Operated By: APT
Ships: APT Ostara, APT Solara (+3 more), MS AmaReina, MS AmaStella, MS AmaVenita
Departures: Jul 2024 to Dec 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+2 more), Hungary, Czech Republic
Flights IncludedLast Minute Deals
Save 1,785
From 12,237
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18 Day Magnificent Europe with Prague with APT
River Cruise
 (5)

18 Days Prague to Amsterdam
Operated By: APT
Ships: APT Ostara, APT Solara (+2 more), MS AmaStella, MS AmaVenita
Departures: Jul 2024 to Dec 2025
Rivers: Danube, Main, Rhine
Countries Visited: Czech Republic, Hungary, Austria, Slovakia (+2 more), Germany, Holland
Flights Included
Save 1,605
From 10,604
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21 Day Magnificent Europe - Paris to Prague with APT
River Cruise
 (10)

21 Days Paris to Prague
Operated By: APT
Ships: APT Ostara, APT Solara (+3 more), MS AmaReina, MS AmaStella, MS AmaVenita
Departures: Sep 2024 to Dec 2025
Rivers: Rhine, Main, Danube
Countries Visited: France, Belgium, Holland, Germany (+4 more), Austria, Slovakia, Hungary, Czech Republic
Flights Included
Save 669
From 15,456
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25 Day Eastern Bloc with Magnificent Europe with APT
River Cruise
 (1)

25 Days Prague to Amsterdam
Operated By: APT
Ships: APT Ostara, MS AmaReina (+1 more), MS AmaVenita
Departures: Sep 2024 to Sep 2025
Rivers: Danube, Main, Rhine
Countries Visited: Czech Republic, Germany, Poland, Hungary (+3 more), Slovakia, Austria, Holland
Flights IncludedLast Minute Deals
Save 1,858
From 19,318
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27 Day Switzerland by Rail with Magnificent Europe with APT
River Cruise
 (1)

27 Days Zurich to Budapest
Operated By: APT
Ships: APT Ostara, APT Solara (+2 more), MS AmaReina, MS AmaVenita
Departures: Jul 2024 to Sep 2025
Rivers: Rhine, Main, Danube
Countries Visited: Switzerland, Holland, Germany, Austria (+2 more), Slovakia, Hungary
Flights Included
Save 772
From 27,733
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25 Day Festive Christmas with Magnificent Europe and Paris with APT
River Cruise

25 Days Berlin to Paris
Operated By: APT
Ships: APT Ostara, MS AmaStella (+1 more), MS AmaVenita
Departures: Dec 2024 to Nov 2025
Rivers: Danube, Main, Rhine
Countries Visited: Germany, Czech Republic, Hungary, Slovakia (+4 more), Austria, Holland, Belgium, France
Flights Included
Save 697
From 21,298
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28 Day Wonders of Scandinavia with Magnificent Europe with APT
River Cruise

28 Days Copenhagen to Budapest
Operated By: APT
Ship: APT Ostara
Departures: Jun 2025 to Aug 2025
Rivers: Rhine, Main, Danube
Countries Visited: Denmark, Norway, Sweden, Holland (+4 more), Germany, Austria, Slovakia, Hungary
Flights Included
Save 748
From 25,753
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27 Day Iconic Italy with Magnificent Europe with APT
River Cruise

27 Days Rome to Amsterdam
Operated By: APT
Ships: APT Solara, MS AmaReina
Departures: Sep 2024 to Sep 2025
Rivers: Danube, Main, Rhine
Countries Visited: Italy, Slovenia, Croatia, Hungary (+4 more), Slovakia, Austria, Germany, Holland
Flights IncludedLast Minute Deals
Save 1,797
From 23,179
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15 Day Magnificent Europe with Christmas and New Years Eve with APT
River Cruise

15 Days Amsterdam to Budapest
Operated By: APT
Ship: APT Ostara
Departure: 19 December 2025
Rivers: Rhine, Main, Danube
Countries Visited: Holland, Germany, Austria, Slovakia (+1 more), Hungary
Flights Included
Save 610
From 12,385
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18 Day Magnificent Europe with Paris with APT
River Cruise

18 Days Paris to Budapest
Operated By: APT
Ships: APT Ostara, APT Solara (+3 more), MS AmaReina, MS AmaStella, MS AmaVenita
Departures: Sep 2024 to Dec 2025
Rivers: Rhine, Main, Danube
Countries Visited: France, Belgium, Holland, Germany (+3 more), Austria, Slovakia, Hungary
Flights Included
Save 649
From 13,475
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22 Day Northern Lights and Lapland with Magnificent Europe with APT
River Cruise

22 Days Helsinki to Amsterdam
Operated By: APT
Ships: APT Ostara, APT Solara
Departures: Nov 2025 to Nov 2025
Rivers: Danube, Main, Rhine
Countries Visited: Finland, Hungary, Slovakia, Austria (+2 more), Germany, Holland
Flights Included
Save 700
From 19,614
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26 Day Emerald Ireland with Magnificent Europe with APT
River Cruise

26 Days Dublin to Budapest
Operated By: APT
Ship: APT Solara
Departures: Jun 2025 to Sep 2025
Rivers: Rhine, Main, Danube
Countries Visited: Ireland, Northern Ireland, Holland, Germany (+3 more), Austria, Slovakia, Hungary
Flights Included
Save 730
From 23,476
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18 Day Magnificent Europe with Paris with APT
River Cruise

18 Days Budapest to Paris
Operated By: APT
Ships: APT Ostara, APT Solara
Departures: May 2025 to Dec 2025
Rivers: Danube, Main, Rhine
Countries Visited: Hungary, Slovakia, Austria, Germany (+3 more), Holland, Belgium, France
Flights Included
Save 649
From 11,891
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