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Central America Luxury Cruises

Explore the best luxury cruises to the Central America. Choose from 81 unique cruise itineraries from 7 leading cruise lines. December is the most popular month to join a luxury cruise to the Central America with 81 departures starting between October 2024 and October 2026.
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81 Cruises (81 Cruise Departures)
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 23 March 2025
Countries Visited: USA, Mexico, Guatemala, Belize (+3 more), Honduras, Costa Rica, Panama
Exclusive Deal
INSIDE
$5,138
OCEANVIEW
$5,514
BALCONY
$7,732
SUITE
$10,266
Save 2,032
From 5,138
View Trip
8 Day Tropical Retreats with Oceania Cruises
Cruise
 (2)

8 Days (7 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 December 2024
Countries Visited: USA, Mexico, Belize, Honduras
Exclusive Deal
INSIDE
$2,784
OCEANVIEW
$2,933
BALCONY
$3,774
SUITE
$5,061
Save 2,016
From 2,784
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 08 February 2025
Countries Visited: USA, Mexico, Belize, Guatemala (+3 more), Honduras, Costa Rica, Panama
Exclusive Deal
INSIDE
$5,465
OCEANVIEW
$5,999
BALCONY
$8,207
SUITE
$10,741
Save 2,035
From 5,465
View Trip
17 Day Beyond The Panama Canal with Oceania Cruises
Cruise
 (1)

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 23 December 2024
Countries Visited: USA, Bahamas, Colombia, Costa Rica (+3 more), Nicaragua, Guatemala, Mexico
Cabin Upgrade Offer
INSIDE
$6,866
OCEANVIEW
$6,866
BALCONY
$8,015
SUITE
$16,182
From 6,866
View Trip
11 Day Western Caribbean Bliss with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Miami to Cartagena
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 03 December 2024
Countries Visited: USA, Mexico, Belize, Guatemala (+4 more), Honduras, Costa Rica, Panama, Colombia
Cabin Upgrade Offer
INSIDE
$3,420
OCEANVIEW
$3,420
BALCONY
$4,113
SUITE
$6,875
From 3,420
View Trip
10 Day Panama Canal Voyage with Azamara Cruises
Cruise
 (1)

10 Days (9 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 13 December 2024
Countries Visited: Panama, Costa Rica, Honduras, Guatemala (+2 more), Mexico, USA
Circle Club Voyage
INSIDE
$3,311
OCEANVIEW
$3,492
BALCONY
$4,268
SUITE
$5,820
From 3,311
View Trip
11 Day Maya Revelations with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Miami to Cartagena
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 01 March 2025
Countries Visited: USA, Mexico, Belize, Honduras (+3 more), Costa Rica, Panama, Colombia
Exclusive Deal
INSIDE
$5,257
OCEANVIEW
$5,792
BALCONY
$7,544
SUITE
$9,316
Save 2,033
From 5,257
View Trip
19 Day San Francisco To Miami with Cunard
Cruise
 (9)

19 Days (18 Nights) San Francisco to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 28 September 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+2 more), Colombia, Aruba
Exclusive Deal
INSIDE
$3,124
OCEANVIEW
$3,569
BALCONY
$4,262
SUITE
$10,895
From 3,124
View Trip
17 Day Fort Lauderdale to Lima with Silversea
Cruise

17 Days (16 Nights) Fort Lauderdale to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 19 December 2024
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Ecuador, Peru
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,949
Save 851
From 9,949
View Trip
19 Day Los Angeles to Fort Lauderdale with Silversea
Cruise

19 Days (18 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 09 May 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Colombia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$13,018
BALCONY
$14,305
SUITE
$24,700
Save 882
From 13,018
View Trip
11 Day Tropical Tastes Of The Riviera with Regent Seven Seas
Cruise

11 Days (10 Nights) Panama City to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 January 2026
Countries Visited: Panama, Costa Rica, Nicaragua, Mexico (+1 more), USA
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,618
SUITE
$10,143
Save 6,132
From 9,618
View Trip
12 Day Panama City to Los Angeles with Silversea
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 24 December 2024
Countries Visited: Panama, Costa Rica, Mexico, USA
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$6,781
BALCONY
$9,256
SUITE
-
Save 819
From 6,781
View Trip
8 Day Rhythms Under The Sun with Regent Seven Seas
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 11 December 2024
Countries Visited: USA, Honduras, Belize, Mexico
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,811
SUITE
$7,692
Save 3,559
From 6,811
View Trip
19 Day Fort Lauderdale to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Silversea
Ship: Silver Moon
Departure: 01 April 2025
Countries Visited: USA, Colombia, Panama, Costa Rica (+2 more), Guatemala, Mexico
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$12,622
BALCONY
$14,107
SUITE
$26,086
Save 878
From 12,622
View Trip
11 Day Puntarenas to Lima with Silversea
Cruise

11 Days (10 Nights) Puntarenas to Lima
Cruise Line: Silversea
Ship: Silver Wind
Departure: 31 October 2024
Countries Visited: Costa Rica, Ecuador, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$9,405
BALCONY
$13,365
SUITE
-
From 9,405
View Trip
10 Day Panama City to Fort Lauderdale with Silversea
Cruise

10 Days (9 Nights) Panama City to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 11 January 2025
Countries Visited: Aruba, Colombia, Panama, USA
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$6,682
From 6,682
View Trip
8 Day Sun-drenched Islands with Regent Seven Seas
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 17 February 2025
Countries Visited: USA, Mexico, Honduras, Belize
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,445
BALCONY
$7,841
SUITE
$8,583
Save 3,405
From 6,445
View Trip
13 Day Fort Lauderdale to Lima with Silversea
Cruise

13 Days (12 Nights) Fort Lauderdale to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 20 January 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+1 more), Peru
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,137
Save 863
From 11,137
View Trip
30 Day Bridgetown to Los Angeles with Silversea
Cruise

30 Days (29 Nights) Bridgetown to Los Angeles
Cruise Line: Silversea
Ship: Silver Moon
Departure: 21 March 2025
Countries Visited: Barbados, Saint Vincent, Saint Lucia, Martinique (+11 more), Sint Maarten, Antigua and Barbuda, Saint Barthelemy, Puerto Rico, Turks and Caicos Islands, USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$15,246
BALCONY
$19,206
SUITE
$33,066
From 15,246
View Trip
9 Day Cartagena to Fort Lauderdale with Silversea
Cruise

9 Days (8 Nights) Cartagena to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Moon
Departure: 29 December 2024
Countries Visited: Belize, Colombia, Honduras, Mexico (+2 more), Panama, USA
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$7,920
BALCONY
$8,712
SUITE
$26,730
From 7,920
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Countries Visited: Bahamas, Colombia, Panama
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,440
SUITE
$12,816
Save 3,605
From 10,440
View Trip
17 Day Stars & Salsa with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 January 2026
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+3 more), Costa Rica, Colombia, Cayman Islands
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,952
SUITE
$15,982
Save 6,778
From 14,952
View Trip
34 Day Los Angeles to New York with Silversea
Cruise

34 Days (33 Nights) Los Angeles to New York
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 09 May 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+7 more), Colombia, Dominican Republic, Jamaica, Aruba, Saint Barthelemy, Virgin Islands, Bermuda
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$13,959
BALCONY
$17,622
SUITE
$31,185
From 13,959
View Trip
17 Day Lima to Fort Lauderdale with Silversea
Cruise

17 Days (16 Nights) Lima to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Peru, Ecuador, Panama, Colombia (+2 more), Aruba, USA
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,127
Save 873
From 12,127
View Trip
8 Day Mayan Magic with Regent Seven Seas
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 06 December 2024
Countries Visited: USA, Mexico, Belize, Honduras
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,136
Save 3,424
From 8,136
View Trip
8 Day Tropical Retreats with Oceania Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 02 March 2025
Countries Visited: USA, Mexico, Belize, Honduras
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$5,140
SUITE
$7,189
Save 2,040
From 5,140
View Trip
8 Day Fort Lauderdale to Panama City with Silversea
Cruise

8 Days (7 Nights) Fort Lauderdale to Panama City
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 17 December 2024
Countries Visited: USA, Colombia, Panama
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$5,148
BALCONY
$6,633
SUITE
-
From 5,148
View Trip
22 Day Seattle To Miami with Cunard
Cruise
 (9)

22 Days (21 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 25 September 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+2 more), Colombia, Aruba
Exclusive Deal
INSIDE
$3,966
OCEANVIEW
$4,461
BALCONY
$5,253
SUITE
$13,668
From 3,966
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Countries Visited: USA, Bahamas, Colombia, Panama
Exclusive DealEarlybird Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$19,939
SUITE
$25,126
Save 7,201
From 19,939
View Trip
18 Day Panama Canal Holiday Voyage with Azamara Cruises
Cruise
 (1)

18 Days (17 Nights) Miami to San Diego
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 20 December 2024
Countries Visited: USA, Colombia, Costa Rica, Guatemala (+1 more), Mexico
INSIDE
$4,798
OCEANVIEW
$5,413
BALCONY
$7,367
SUITE
-
From 4,798
View Trip
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