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Cruises from Malta to Spain

Are you looking for a cruise from Malta to Spain? October is the most popular month to cruise between Malta and Spain and there are 19 departures available from five of the world's leading cruise lines.
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3 Days
17 Days
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17 Cruises (19 Cruise Departures)
13 Day Palazzi & Rivieras with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Valletta to Malaga
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 25 September 2025
Countries Visited: Malta, Tunisia, Sicily, Italy (+3 more), Corsica, France, Spain
Exclusive Deal
INSIDE
$5,728
OCEANVIEW
$6,481
BALCONY
$9,639
SUITE
$13,628
Save (per person) 2,042
From (per person) 5,728
View Trip
11 Day Romantic Mediterranean with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Valletta to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 20 September 2026
Countries Visited: Malta, Sicily, Italy, Sardinia (+2 more), France, Spain
Exclusive Deal
INSIDE
$4,825
OCEANVIEW
$5,280
BALCONY
$7,983
SUITE
$10,992
Save (per person) 2,035
From (per person) 4,825
View Trip
10 Day Ancient shores of the Mediterranean with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Malaga
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 12 December 2025
Countries Visited: Malta, Sicily, Tunisia, Algeria (+1 more), Spain
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,726
SUITE
$15,674
Save (per person) 164
From (per person) 8,726
View Trip
16 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

16 Days (15 Nights) Valletta to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 02 October 2025
Countries Visited: Malta, Italy, France, Corsica (+2 more), Spain, Morocco
Latest Offer
INSIDE
$1,874
OCEANVIEW
$2,350
BALCONY
$3,011
SUITE
-
From (per person) 1,874
View Trip
12 Day Valletta to Barcelona with Silversea
Cruise

12 Days (11 Nights) Valletta to Barcelona
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 17 August 2025
Countries Visited: Malta, Sicily, Italy, France (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,395
BALCONY
$12,969
SUITE
$18,810
Save (per person) 4,905
From (per person) 10,395
View Trip
15 Day Moroccan & Spanish Delights with Oceania Cruises
Cruise

15 Days (14 Nights) Valletta to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 22 August 2026
Countries Visited: Malta, Tunisia, Spain, Portugal (+1 more), Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,096
SUITE
$15,957
Save (per person) 2,084
From (per person) 10,096
View Trip
16 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

16 Days (15 Nights) Valletta to Santa Cruz De Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 08 October 2026
Countries Visited: Malta, Spain, Morocco, Portugal
Latest Offer
INSIDE
$1,746
OCEANVIEW
$2,042
BALCONY
$2,832
SUITE
-
From (per person) 1,746
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Valletta to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 02 October 2025
Countries Visited: Malta, Spain
Holiday Breaks Offer
INSIDE
-
OCEANVIEW
$483
BALCONY
$730
SUITE
$978
From (per person) 483
View Trip
17 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

17 Days (16 Nights) Valletta to Santa Cruz De Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 01 October 2026
Countries Visited: Malta, France, Italy, Spain (+1 more), Morocco
Latest Offer
INSIDE
$2,162
OCEANVIEW
$2,547
BALCONY
$3,357
SUITE
-
From (per person) 2,162
View Trip
9 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

9 Days (8 Nights) Valletta to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Oct 2025 to Oct 2026
Countries Visited: Malta, Spain, Morocco
Latest Offer
INSIDE
$764
OCEANVIEW
$1,012
BALCONY
$1,486
SUITE
$2,525
From (per person) 764
View Trip
16 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

16 Days (15 Nights) Valletta to Santa Cruz De Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 01 October 2026
Countries Visited: Malta, France, Italy, Spain (+1 more), Morocco
Latest Offer
INSIDE
$2,072
OCEANVIEW
$2,507
BALCONY
$3,109
SUITE
-
From (per person) 2,072
View Trip
17 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

17 Days (16 Nights) Valletta to Santa Cruz De Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 08 October 2026
Countries Visited: Malta, Spain, Morocco, Portugal
Latest Offer
INSIDE
$1,885
OCEANVIEW
$2,250
BALCONY
$2,981
SUITE
-
From (per person) 1,885
View Trip
16 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

16 Days (15 Nights) Valletta to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 09 October 2025
Countries Visited: Malta, Spain, Morocco, Portugal
Latest Offer
INSIDE
$1,647
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 1,647
View Trip
10 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

10 Days (9 Nights) Valletta to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Oct 2025 to Oct 2026
Countries Visited: Malta, Spain, Morocco
Latest Offer
INSIDE
$913
OCEANVIEW
$1,131
BALCONY
$1,763
SUITE
$2,981
From (per person) 913
View Trip
17 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

17 Days (16 Nights) Valletta to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 09 October 2025
Countries Visited: Malta, Spain, Morocco, Portugal
Latest Offer
INSIDE
$1,617
OCEANVIEW
$2,161
BALCONY
$2,873
SUITE
-
From (per person) 1,617
View Trip
17 Day Mediterranean And Canary Islands with P&O Cruises Worldwide
Cruise

17 Days (16 Nights) Valletta to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 02 October 2025
Countries Visited: Malta, Italy, France, Corsica (+2 more), Spain, Morocco
Latest Offer
INSIDE
$1,865
OCEANVIEW
$2,507
BALCONY
$3,467
SUITE
-
From (per person) 1,865
View Trip
8 Day Cruising the Mediterranean: Sicily, Sardinia, and Mallorca - with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Valletta to Tarragona
Cruise Line: Ponant
Ship: L'Austral
Departure: 03 October 2025
Countries Visited: Malta, Sicily, Sardinia, Spain
Exclusive Savings
INSIDE
-
OCEANVIEW
$8,066
BALCONY
$8,683
SUITE
$13,035
Save (per person) 154
From (per person) 8,066
View Trip
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