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P&O (UK) Cruises from Santa Cruz de Tenerife

Start your journey from Santa Cruz de Tenerife with 35 unique P&O (UK) cruise itineraries to choose from. December is the most popular month to begin your cruise from Santa Cruz de Tenerife and P&O Cruises Worldwide have 168 trips departing this season.
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8 Days
28 Days
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35 Cruises (168 Cruise Departures)
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 13 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,112
OCEANVIEW
$3,834
BALCONY
$4,931
SUITE
$7,704
From (per person) 3,112
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$665
OCEANVIEW
$932
BALCONY
$1,426
SUITE
$2,079
From (per person) 665
View Trip
21 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 13 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
Latest Offer
INSIDE
$2,619
OCEANVIEW
$3,330
BALCONY
$4,270
SUITE
-
From (per person) 2,619
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$665
OCEANVIEW
$932
BALCONY
$1,426
SUITE
$2,060
From (per person) 665
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 25 October 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,369
OCEANVIEW
$2,696
BALCONY
$3,674
SUITE
-
From (per person) 2,369
View Trip
28 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

28 Days (27 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+3 more), Malta, France, Croatia
Latest Offer
INSIDE
$5,462
OCEANVIEW
$6,401
BALCONY
$7,687
SUITE
-
From (per person) 5,462
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

20 Days (19 Nights) Santa Cruz De Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 13 March 2027
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
Latest Offer
INSIDE
$2,509
OCEANVIEW
$3,191
BALCONY
$3,854
SUITE
-
From (per person) 2,509
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 17 October 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,369
OCEANVIEW
$2,795
BALCONY
$3,674
SUITE
$8,249
From (per person) 2,369
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Feb 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,696
OCEANVIEW
$1,983
BALCONY
$2,753
SUITE
$5,130
From (per person) 1,696
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 20 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,805
OCEANVIEW
$4,280
BALCONY
$5,278
SUITE
-
From (per person) 3,805
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,696
OCEANVIEW
$1,904
BALCONY
$2,634
SUITE
$4,604
From (per person) 1,696
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 19 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,805
OCEANVIEW
$4,181
BALCONY
$5,278
SUITE
-
From (per person) 3,805
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 31 October 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,191
OCEANVIEW
$2,478
BALCONY
$3,426
SUITE
$7,872
From (per person) 2,191
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Feb 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,696
OCEANVIEW
$1,983
BALCONY
$2,753
SUITE
$4,388
From (per person) 1,696
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,754
OCEANVIEW
$2,051
BALCONY
$2,644
SUITE
$4,317
From (per person) 1,754
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 19 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,635
OCEANVIEW
$1,922
BALCONY
$2,644
SUITE
$4,317
From (per person) 1,635
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 24 October 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,189
OCEANVIEW
$1,457
BALCONY
$1,832
SUITE
-
From (per person) 1,189
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 12 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,112
OCEANVIEW
$3,983
BALCONY
$4,931
SUITE
$7,704
From (per person) 3,112
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 01 November 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,191
OCEANVIEW
$2,379
BALCONY
$3,426
SUITE
-
From (per person) 2,191
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Oct 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$665
OCEANVIEW
$932
BALCONY
$1,426
SUITE
$2,079
From (per person) 665
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,112
OCEANVIEW
$3,983
BALCONY
$4,931
SUITE
$11,268
From (per person) 3,112
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 20 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,635
OCEANVIEW
$1,922
BALCONY
$2,644
SUITE
-
From (per person) 1,635
View Trip
21 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+2 more), Malta, France
Latest Offer
INSIDE
$3,757
OCEANVIEW
$4,657
BALCONY
$5,785
SUITE
$10,151
From (per person) 3,757
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$3,329
OCEANVIEW
$3,834
BALCONY
$4,931
SUITE
-
From (per person) 3,329
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

20 Days (19 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 14 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
Latest Offer
INSIDE
$2,490
OCEANVIEW
$3,083
BALCONY
$3,765
SUITE
-
From (per person) 2,490
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,833
OCEANVIEW
$2,298
BALCONY
$2,644
SUITE
-
From (per person) 1,833
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2025 to Mar 2027
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$1,646
OCEANVIEW
$1,904
BALCONY
$2,634
SUITE
$4,159
From (per person) 1,646
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

20 Days (19 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 21 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+2 more), Malta, France
Latest Offer
INSIDE
$3,876
OCEANVIEW
$4,508
BALCONY
$5,566
SUITE
$9,685
From (per person) 3,876
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 18 October 2025
Countries Visited: Spain, Portugal
Latest Offer
INSIDE
$2,369
OCEANVIEW
$2,795
BALCONY
$3,674
SUITE
-
From (per person) 2,369
View Trip
27 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

27 Days (26 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 21 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+3 more), Malta, France, Croatia
Latest Offer
INSIDE
$5,106
OCEANVIEW
$5,836
BALCONY
$7,489
SUITE
-
From (per person) 5,106
View Trip
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