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MSC Cruises from Santos

Start your journey from Santos with 28 unique MSC cruise itineraries to choose from. April is the most popular month to begin your cruise from Santos and MSC Cruises have 52 trips departing this season.
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25 Days
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28 Cruises (52 Cruise Departures)
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Countries Visited: Brazil, Spain, Gibraltar, France
Early Booking OfferSeasational Sale
INSIDE
$2,154
OCEANVIEW
$2,461
BALCONY
$2,906
SUITE
$4,520
From (per person) 2,154
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Countries Visited: Brazil, Spain, Gibraltar, France (+1 more), Italy
Early Booking OfferSeasational Sale
INSIDE
$2,287
OCEANVIEW
$2,593
BALCONY
$3,069
SUITE
$4,771
From (per person) 2,287
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Countries Visited: Brazil, Spain, Gibraltar
Early Booking Offer
INSIDE
$2,002
OCEANVIEW
$2,260
BALCONY
$2,676
SUITE
$4,180
From (per person) 2,002
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 26 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$2,612
OCEANVIEW
$2,889
BALCONY
$3,315
SUITE
$3,988
From (per person) 2,612
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Santos to Santiago De Compostela
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain
Early Booking Offer
INSIDE
$1,979
OCEANVIEW
$2,207
BALCONY
$2,435
SUITE
-
From (per person) 1,979
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise

25 Days (24 Nights) Santos to Hamburg
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+5 more), France, Belgium, Denmark, Norway, Germany
Early Booking Offer
INSIDE
$3,418
OCEANVIEW
$3,784
BALCONY
$4,170
SUITE
$12,745
From (per person) 3,418
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Copenhagen
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+3 more), France, Belgium, Denmark
Early Booking Offer
INSIDE
-
OCEANVIEW
$3,418
BALCONY
$4,190
SUITE
$11,146
From (per person) 3,418
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 15 March 2026
Countries Visited: Brazil, Cape Verde, Spain, Morocco (+1 more), Italy
Early Booking Offer
INSIDE
$2,223
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 2,223
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Santos to Oslo
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+4 more), France, Belgium, Denmark, Norway
Early Booking Offer
INSIDE
$3,144
OCEANVIEW
$3,580
BALCONY
$4,342
SUITE
-
From (per person) 3,144
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Feb 2025 to Mar 2025
Countries Visited: Brazil, Argentina, Uruguay
Early Booking Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$2,074
SUITE
$2,757
From (per person) 2,074
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Santos to Honfleur
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+1 more), France
Early Booking OfferSeasational Sale
INSIDE
$2,547
OCEANVIEW
$2,854
BALCONY
$3,616
SUITE
$6,616
From (per person) 2,547
View Trip
13 Day MSC Grand Voyages with MSC Cruises
Cruise

13 Days (12 Nights) Santos to Funchal
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal
Early Booking Offer
INSIDE
$1,715
OCEANVIEW
$1,903
BALCONY
$2,378
SUITE
-
From (per person) 1,715
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 23 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
-
OCEANVIEW
$1,566
BALCONY
$1,665
SUITE
$2,397
From (per person) 1,566
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 13 March 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$816
OCEANVIEW
-
BALCONY
-
SUITE
$1,538
From (per person) 816
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 13 February 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,470
OCEANVIEW
-
BALCONY
-
SUITE
$2,698
From (per person) 1,470
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 17 January 2026
Countries Visited: Brazil, Argentina, Uruguay
Early Booking Offer
INSIDE
$1,444
OCEANVIEW
-
BALCONY
$2,117
SUITE
$2,919
From (per person) 1,444
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departures: Dec 2025 to Jan 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,282
OCEANVIEW
-
BALCONY
-
SUITE
$2,450
From (per person) 1,282
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 22 February 2026
Countries Visited: Brazil, Argentina, Uruguay
Early Booking Offer
INSIDE
$1,282
OCEANVIEW
$1,520
BALCONY
$1,698
SUITE
$2,569
From (per person) 1,282
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 06 February 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$816
OCEANVIEW
-
BALCONY
-
SUITE
$1,538
From (per person) 816
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Lirica
Departures: Mar 2025 to Jan 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$687
OCEANVIEW
$1,212
BALCONY
-
SUITE
$1,410
From (per person) 687
View Trip
6 Day South America with MSC Cruises
Cruise

6 Days (5 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 27 February 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
-
OCEANVIEW
$1,482
BALCONY
-
SUITE
-
From (per person) 1,482
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Jan 2026 to Mar 2026
Countries Visited: Brazil, Uruguay, Argentina
Early Booking Offer
INSIDE
$1,223
OCEANVIEW
$1,430
BALCONY
$1,619
SUITE
$2,490
From (per person) 1,223
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to London
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Countries Visited: Brazil, Portugal, Spain, England
Early Booking OfferSeasational Sale
INSIDE
$2,405
OCEANVIEW
$2,742
BALCONY
$3,326
SUITE
$6,167
From (per person) 2,405
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Preziosa
Departures: Jan 2026 to Mar 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$766
OCEANVIEW
$895
BALCONY
$994
SUITE
$1,529
From (per person) 766
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 15 March 2026
Countries Visited: Brazil, Cape Verde, Spain, Morocco (+4 more), Italy, Sicily, Malta, Croatia
Early Booking Offer
INSIDE
$2,913
OCEANVIEW
$3,497
BALCONY
-
SUITE
-
From (per person) 2,913
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Dec 2025 to Dec 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$476
OCEANVIEW
$624
BALCONY
$674
SUITE
$1,119
From (per person) 476
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departures: Nov 2025 to Dec 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$796
OCEANVIEW
$915
BALCONY
$1,014
SUITE
$1,538
From (per person) 796
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 29 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,975
OCEANVIEW
-
BALCONY
-
SUITE
$3,212
From (per person) 1,975
View Trip
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