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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 245 unique cruise itineraries to Sicily, departing from Athens, Barcelona, Florence, Genoa, Istanbul and more. October is the most popular month to cruise to Sicily and we have over 1,341 departures available from twenty of the world's leading cruise lines.
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245 Cruises (1,341 Cruise Departures)
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Rome
Ship: Norwegian Epic
Departure: 22 September 2025
Countries Visited: Italy, Greece, Sicily
INSIDE
$3,393
OCEANVIEW
-
BALCONY
$5,304
SUITE
$5,382
From 3,393
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12 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (1)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 15 July 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,012
OCEANVIEW
$5,502
BALCONY
$6,192
SUITE
$8,261
From 5,012
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8 Day Glorious Greek Isles to Spanish Sunsets with Virgin Voyages
Cruise
 (4)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 20 October 2024
Countries Visited: Greece, Sicily, Spain
INSIDE
$1,892
OCEANVIEW
$2,040
BALCONY
$2,116
SUITE
$4,131
From 1,892
View Trip
9 Day A Circumnavigation of Sicily - with Smithsonian Journeys with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departures: Jun 2025 to Aug 2025
Countries Visited: Malta, Sicily, Tunisia
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,067
SUITE
$17,103
Save 206
From 10,067
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13 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (1)

13 Days (12 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 11 April 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,230
OCEANVIEW
$5,951
BALCONY
$6,640
SUITE
$9,054
From 5,230
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8 Day Ancient Wonders and Culinary Delights: Cruising Southern Italy and Sicily - with Smithsonian Journey with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Livorno
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 September 2024
Countries Visited: Malta, Sicily, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,692
SUITE
-
Save 208
From 10,692
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8 Day Islands and Cities of the Mediterranean with Ponant
Cruise
 (1)

8 Days (7 Nights) Athens to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 23 July 2024
Countries Visited: Greece, Sicily, Malta
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$7,468
SUITE
$16,376
Save 142
From 7,468
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8 Day Greece & Italy Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 15 August 2025
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$1,700
OCEANVIEW
$1,974
BALCONY
$2,389
SUITE
$3,501
Save 733
From 1,561
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10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: May 2026 to Jul 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$9,747
BALCONY
-
SUITE
$13,261
Save 2,102
From 9,747
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11 Day Mediterranean Delights with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 20 July 2026
Countries Visited: Malta, Sicily, Tunisia
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,588
BALCONY
-
SUITE
$14,548
Save 2,607
From 10,588
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4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia, Sicily
Exclusive Deal
INSIDE
$609
OCEANVIEW
-
BALCONY
$807
SUITE
$1,075
From 609
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8 Day Greece & Spain with Royal Caribbean
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 26 August 2024
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$2,357
OCEANVIEW
$2,726
BALCONY
$2,451
SUITE
$4,328
Save 828
From 1,746
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9 Day A Journey To Soulful Sicily And Southern Greece with Explora Journeys
Cruise

9 Days (8 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 19 June 2024
Countries Visited: Spain, Sicily, Malta
Unique EscapesExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,237
SUITE
$8,791
From 7,237
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 11 July 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$9,747
BALCONY
-
SUITE
$13,261
Save 2,098
From 9,747
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+5 more), Viking Saturn, Viking Sky, Viking Star, Viking Venus, Viking Vesta
Departures: Aug 2024 to Aug 2026
Countries Visited: Italy, Sicily, Croatia
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,945
SUITE
$7,420
Save 1,125
From 4,945
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8 Day Island Odyssey: Malta, Sicily & the Greek Isles with Scenic
New ReleaseCruise

8 Days (7 Nights) Valletta to Athens
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 June 2026
Countries Visited: Malta, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,143
SUITE
$16,177
Save 3,102
From 10,143
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6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 26 April 2025
Countries Visited: Italy, Sicily, Spain
Exclusive Deal
INSIDE
$784
OCEANVIEW
$913
BALCONY
$1,081
SUITE
$2,111
From 784
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+4 more), Viking Saturn, Viking Vela, Viking Venus, Viking Vesta
Departures: Jul 2024 to Sep 2026
Countries Visited: Italy, Croatia, Sicily
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$5,935
SUITE
$10,390
Save 1,279
From 5,935
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Southbound with Tauck
Cruise

12 Days (11 Nights) Rome to Valletta
Operated By: Tauck
Departures: Jun 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Italy, Sicily, Malta
From 18,170
View Trip
7 Day Greece, Italy & Spain Cruise with Royal Caribbean
Cruise

7 Days (6 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 27 October 2024
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$1,428
OCEANVIEW
-
BALCONY
-
SUITE
$2,941
Save 631
From 1,289
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 05 October 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
$2,169
OCEANVIEW
$2,763
BALCONY
$2,967
SUITE
$4,515
Save 884
From 1,865
View Trip
12 Day Along the Mediterranean Sea with the Mucem with Ponant
Cruise

12 Days (11 Nights) Athens to Lisbon
Cruise Line: Ponant
Ship: L'Austral
Departure: 10 October 2024
Countries Visited: Greece, Sicily, Sardinia
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$12,433
SUITE
$26,231
Save 237
From 12,433
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Malta, Sicily, Italy
From 18,940
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 07 June 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,890
Save 2,090
From 8,890
View Trip
11 Day Amalfi Coast, Sicily & Gulf of Naples with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 October 2024
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,301
Save 3,144
From 14,301
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8 Day Italian Treasures: Amalfi Coast, Sicily and Malta with Scenic
New ReleaseCruise

8 Days (7 Nights) Rome to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 07 June 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,291
SUITE
$16,325
Save 3,104
From 10,291
View Trip
8 Day Greece & Spain with Royal Caribbean
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 01 July 2024
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$2,475
OCEANVIEW
-
BALCONY
-
SUITE
-
Save 806
From 1,688
View Trip
8 Day Italian & Aegean Sampler with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 30 April 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$4,644
SUITE
$7,297
Save 2,036
From 4,644
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 July 2025
Countries Visited: Greece, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,579
BALCONY
-
SUITE
$8,890
Save 1,566
From 6,579
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8 Day Highlights of Southern Italy with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 29 June 2024
Countries Visited: Italy, Sicily, Croatia
Exclusive Savings
INSIDE
-
OCEANVIEW
$7,359
BALCONY
-
SUITE
$10,343
Save 136
From 7,359
View Trip
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