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MSC South America Cruises

MSC South America Cruises

Join MSC on one of 92 cruises visiting the coastal ports and cities of South America this season. December is the most popular month to begin your cruise and MSC have 243 cruises departing between February 2025 and April 2026.
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4 Days
27 Days
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$400pp
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92 Cruises (243 Cruise Departures)
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Feb 2025 to Mar 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$1,143
OCEANVIEW
$1,371
BALCONY
$1,727
SUITE
$2,371
From (per person) 1,143
View Trip
11 Day South America with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 26 December 2025
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$2,787
OCEANVIEW
$3,144
BALCONY
$3,540
SUITE
$4,629
From (per person) 2,787
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

21 Days (20 Nights) Buenos Aires to Marseille
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 23 March 2026
Countries Visited: Argentina, Brazil, Spain, Morocco (+1 more), France
Early Booking Offer
INSIDE
$2,920
OCEANVIEW
$3,247
BALCONY
$3,613
SUITE
$6,533
From (per person) 2,920
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Nov 2025 to Mar 2026
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$1,395
OCEANVIEW
$1,701
BALCONY
$1,949
SUITE
$2,870
From (per person) 1,395
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

19 Days (18 Nights) Rome to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 06 November 2025
Countries Visited: Italy, Spain, Morocco, Brazil (+2 more), Uruguay, Argentina
Early Booking OfferSeasational Sale
INSIDE
$2,358
OCEANVIEW
$2,655
BALCONY
$3,229
SUITE
$6,041
From (per person) 2,358
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Buenos Aires to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 23 March 2026
Countries Visited: Argentina, Brazil, Spain, Morocco (+2 more), France, Italy
Early Booking Offer
INSIDE
$3,072
OCEANVIEW
$3,408
BALCONY
$4,091
SUITE
$6,368
From (per person) 3,072
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

23 Days (22 Nights) Buenos Aires to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 23 March 2026
Countries Visited: Argentina, Brazil, Spain, Morocco (+2 more), France, Italy
Early Booking Offer
INSIDE
$3,194
OCEANVIEW
$3,550
BALCONY
$3,956
SUITE
$6,629
From (per person) 3,194
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Barcelona to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 08 November 2025
Countries Visited: Spain, Morocco, Brazil, Uruguay (+1 more), Argentina
Early Booking OfferSeasational Sale
INSIDE
$2,124
OCEANVIEW
$2,381
BALCONY
$2,668
SUITE
$4,618
From (per person) 2,124
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2026 to Mar 2026
Countries Visited: Uruguay, Argentina, Brazil
Early Booking Offer
INSIDE
$1,744
OCEANVIEW
$2,091
BALCONY
$2,447
SUITE
$3,437
From (per person) 1,744
View Trip
11 Day South America with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 December 2025
Countries Visited: Uruguay, Argentina, Brazil
Early Booking Offer
INSIDE
$2,767
OCEANVIEW
$3,144
BALCONY
$3,540
SUITE
$4,629
From (per person) 2,767
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 11 April 2026
Countries Visited: Brazil, Spain, Gibraltar
Early Booking Offer
INSIDE
$2,002
OCEANVIEW
$2,260
BALCONY
$2,676
SUITE
$4,180
From (per person) 2,002
View Trip
27 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

27 Days (26 Nights) Trieste to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 29 October 2025
Countries Visited: Italy, Croatia, Greece, Malta (+6 more), Sicily, Spain, Morocco, Brazil, Uruguay, Argentina
Early Booking Offer
INSIDE
$3,740
OCEANVIEW
$4,096
BALCONY
$4,928
SUITE
$7,759
From (per person) 3,740
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 13 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,348
OCEANVIEW
$1,566
BALCONY
$1,793
SUITE
$2,437
From (per person) 1,348
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2026 to Mar 2026
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$1,744
OCEANVIEW
$2,091
BALCONY
$2,269
SUITE
$3,437
From (per person) 1,744
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 20 March 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$786
OCEANVIEW
-
BALCONY
$1,103
SUITE
$2,013
From (per person) 786
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 26 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$2,612
OCEANVIEW
$2,889
BALCONY
$3,315
SUITE
$3,988
From (per person) 2,612
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 16 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,368
OCEANVIEW
$1,566
BALCONY
$1,793
SUITE
$3,011
From (per person) 1,368
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 23 March 2026
Countries Visited: Argentina, Brazil, Spain, Morocco
Early Booking OfferSeasational Sale
INSIDE
$2,392
OCEANVIEW
$2,699
BALCONY
$3,313
SUITE
$5,382
From (per person) 2,392
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 02 March 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$1,717
OCEANVIEW
$1,569
BALCONY
$1,994
SUITE
$3,103
From (per person) 1,569
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Sao Paulo to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 18 April 2025
Countries Visited: Brazil, Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$2,629
SUITE
$4,025
From (per person) 2,629
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

21 Days (20 Nights) Montevideo to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 22 March 2026
Countries Visited: Uruguay, Argentina, Brazil, Spain (+1 more), Morocco
Early Booking Offer
INSIDE
$2,910
OCEANVIEW
$3,237
BALCONY
$3,880
SUITE
$6,058
From (per person) 2,910
View Trip
24 Day Mediterranean with MSC Cruises
Cruise
 (1)

24 Days (23 Nights) Bari to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 01 November 2025
Countries Visited: Italy, Greece, Malta, Sicily (+5 more), Spain, Morocco, Brazil, Uruguay, Argentina
Early Booking Offer
INSIDE
$3,319
OCEANVIEW
$3,636
BALCONY
$4,428
SUITE
-
From (per person) 3,319
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 29 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$2,622
OCEANVIEW
$2,889
BALCONY
$3,186
SUITE
-
From (per person) 2,622
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Mar 2025 to Mar 2025
Countries Visited: Brazil, Uruguay, Argentina
Save And Sail Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$1,727
SUITE
$2,371
From (per person) 1,727
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Nov 2025 to Mar 2026
Countries Visited: Uruguay, Argentina, Brazil
Early Booking Offer
INSIDE
$1,404
OCEANVIEW
$1,692
BALCONY
$1,998
SUITE
$2,870
From (per person) 1,404
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Rio de Janeiro to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 09 March 2025
Countries Visited: Brazil, Cape Verde, Spain, Morocco
Early Booking Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$2,735
SUITE
-
From (per person) 2,735
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Rio de Janeiro to Brugge
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 03 April 2026
Countries Visited: Brazil, Portugal, Spain, England (+2 more), France, Belgium
Early Booking Offer
INSIDE
$2,547
OCEANVIEW
$2,933
BALCONY
$3,616
SUITE
-
From (per person) 2,547
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Maceio to Maceio
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departures: Jan 2026 to Mar 2026
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,232
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 1,232
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Buenos Aires to London
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 03 April 2025
Countries Visited: Argentina, Uruguay, Brazil, Spain (+2 more), Portugal, England
Save And Sail Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,144
SUITE
-
From (per person) 5,144
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Rio de Janeiro to London
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 03 April 2026
Countries Visited: Brazil, Portugal, Spain, England
Early Booking OfferSeasational Sale
INSIDE
$2,273
OCEANVIEW
$2,530
BALCONY
$3,223
SUITE
$4,738
From (per person) 2,273
View Trip
Results: 1-30 of 92

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