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All South America Tour & Cruise Packages

Compare 47 tour and cruise packages to South America. Guided land journeys combined seamlessly with cruises exploring the islands of the Galapagos, the Amazon and Antarctica. Travel with the world's leading South American specialists and expedition cruise lines.
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37 Days
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$7,100pp
$88,340pp
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47 Packages (328 Package Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 272
From (per person) 16,956
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 256
From (per person) 14,564
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Mar 2025 to Mar 2026
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save (per person) 269
From (per person) 7,140
View Trip
26 Day South American Discovery with Santiago Stopover & Galápagos Cruise with Globus
Tour + Cruise

26 Days Santiago to Guayaquil
Operated By: Globus
Departures: Jul 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save (per person) 552
From (per person) 19,611
View Trip
34 Day Machu Picchu, Amazon & Antarctic Odyssey - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

34 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 12 January 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Countries Visited: Peru, Argentina, Falkland Islands, South Georgia Island (+1 more), Antarctica
Super EarlybirdExclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$69,301
SUITE
$70,010
Save (per person) 1,299
From (per person) 69,301
View Trip
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 14 February 2026
Trip Styles: Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$26,163
SUITE
$27,499
Save (per person) 2,632
From (per person) 26,163
View Trip
36 Day Antarctic Voyage with South America and Galapagos Islands with APT
Tour + Cruise

36 Days Guayaquil to Rio de Janeiro
Operated By: APT
Ship: Seabourn Venture
Departure: 01 February 2026
Trip Styles: Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru, Argentina (+2 more), Antarctica, Brazil
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$56,510
SUITE
$57,847
Save (per person) 2,885
From (per person) 56,510
View Trip
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Jul 2025 to Nov 2025
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 10,865
View Trip
20 Day Antarctic Voyage with Brazil Highlights with APT
Tour + Cruise

20 Days Buenos Aires to Rio de Janeiro
Operated By: APT
Ship: Seabourn Venture
Departure: 17 February 2026
Trip Styles: Cruise, Scenic
Countries Visited: Argentina, Antarctica, Brazil
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$28,542
SUITE
$29,879
Save (per person) 2,653
From (per person) 28,542
View Trip
21 Day Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey with Scenic
Tour + Cruise

21 Days Rio de Janeiro to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Eclipse II
Departures: Dec 2025 to Jan 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Brazil, Argentina, Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$36,597
SUITE
$42,067
Save (per person) 5,378
From (per person) 36,597
View Trip
24 Day Antarctic Voyage with Peru with APT
New ReleaseTour + Cruise

24 Days Lima to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 08 February 2026
Trip Style: Cruise
Countries Visited: Peru, Argentina, Antarctica
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$30,532
SUITE
$31,869
Save (per person) 2,663
From (per person) 30,532
View Trip
18 Day Land of the Incas with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

18 Days Lima to Quito
Operated By: Trafalgar
Departures: Jun 2025 to Nov 2025
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 15,110
View Trip
17 Day Mysteries of the Inca Empire with a Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: May 2025 to Dec 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Deal
Save (per person) 228
From (per person) 10,157
View Trip
26 Day Wonders of Machu Picchu, the Amazon & Antarctica - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Buenos Aires to Lima
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 15 January 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Countries Visited: Argentina, Antarctica, Peru
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$86,532
SUITE
$96,482
Save (per person) 1,808
From (per person) 86,532
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Operated By: Globus
Departures: Sep 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 559
From (per person) 20,390
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Countries Visited: Peru, Chile, Argentina
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$40,574
SUITE
$46,514
Save (per person) 6,856
From (per person) 40,574
View Trip
30 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Aug 2025 to Sep 2025
Trip Styles: Coach, Cruise, River Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$40,052
Save (per person) 2,343
From (per person) 40,052
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 25,790
View Trip
31 Day Antarctic Voyage with Galápagos and Peru with APT
New ReleaseTour + Cruise

31 Days Guayaquil to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 01 February 2026
Trip Styles: Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos, Peru, Argentina (+1 more), Antarctica
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$50,559
SUITE
$51,896
Save (per person) 2,836
From (per person) 50,559
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: May 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Deal
Save (per person) 240
From (per person) 11,991
View Trip
27 Day Treasures of South America: Chilean Fjords to the Iguazu falls - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

27 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Argentina, Chile, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$27,577
SUITE
$30,151
Save (per person) 6,728
From (per person) 27,577
View Trip
29 Day Ultimate Journey: Patagonia, Argentina, Brazil & Antarctica - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

29 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse I
Departures: Feb 2026 to Jan 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica, Brazil
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$61,143
SUITE
$66,722
Save (per person) 5,594
From (per person) 61,143
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: Oct 2025 to Nov 2025
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From (per person) 17,621
View Trip
15 Day Galapagos & Amazon (Archipel I) with Exodus Adventure Travels
Tour + Cruise

15 Days Quito to Guayaquil
Departures: Jun 2025 to Oct 2025
Trip Styles: Adventure, Small Group, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 374
From (per person) 18,323
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Mar 2025 to Oct 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 21,350
View Trip
13 or 14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

13 or 14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Feb 2025 to Mar 2026
Trip Styles: Adventure, Coach, Small Group, Cruise, Scenic
Countries Visited: Argentina, Chile
Flash Deal
Save (per person) 1,635
From (per person) 11,228
View Trip
13 Day Highlights of Peru with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Jun 2025 to Dec 2025
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 10,865
View Trip
29 Day Antarctic Voyage with South American Discovery with APT
Tour + Cruise

29 Days Lima to Rio de Janeiro
Operated By: APT
Ship: Seabourn Venture
Departure: 08 February 2026
Trip Styles: Cruise, Scenic
Countries Visited: Peru, Argentina, Antarctica, Brazil
Exclusive DealBusiness Class Included + Save
INSIDE
-
OCEANVIEW
-
BALCONY
$35,394
SUITE
$36,730
Save (per person) 2,701
From (per person) 35,394
View Trip
33 Day Southern Expedition: Antarctica, Peru & the Amazon - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

33 Days Buenos Aires to Cusco
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 08 January 2027
Trip Styles: Coach, Cruise, Wildlife, Scenic
Countries Visited: Peru, Argentina, Falkland Islands, South Georgia Island (+1 more), Antarctica
Super Earlybird
INSIDE
-
OCEANVIEW
-
BALCONY
$62,943
SUITE
$73,428
Save (per person) 9,577
From (per person) 62,943
View Trip
23 Day Legacy of the Incas with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

23 Days Lima to Guayaquil
Operated By: Globus
Departures: Apr 2025 to Sep 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Deal
Save (per person) 546
From (per person) 17,921
View Trip
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