All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 1,806 expeditions and cruises around South America travelling with the world's leading cruise lines.
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4 Days
134 Days
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$500pp
$124,495pp
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314 Cruises (1,806 Cruise Departures)
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2024
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 15,892
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 218
From 10,190
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 2,616
From 4,152
Tour + Cruise
 (1)

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Mar 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Brazil, Argentina, Uruguay, Falkland Islands (+2 more), Chile, Peru
Exclusive Deal
Save 1,544
From 17,256
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Feb 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+2 more), Brazil, Peru
Exclusive Deal
Save 1,546
From 16,955
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 4,218
From 9,698
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 4,090
From 6,308
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2024
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 13,877
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Departure: 19 December 2024
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$4,113
OCEANVIEW
-
BALCONY
$5,422
SUITE
$6,558
From 4,113
Cruise
 (1)

18 Days (17 Nights) San Antonio to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Cayman Islands, USA
Have It All Offer
INSIDE
$4,590
OCEANVIEW
$4,749
BALCONY
$6,105
SUITE
$8,817
From 4,590
Cruise
 (1)

11 Days (10 Nights) Lima to San Antonio
Cruise Line: Azamara Cruises
Departure: 23 January 2025
Countries Visited: Peru, Chile
Circle Club Voyage
INSIDE
$3,856
OCEANVIEW
$4,461
BALCONY
$5,150
SUITE
$7,909
From 3,856
Cruise
 (1)

10 Days (9 Nights) Hanga Roa to Ushuaia
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 November 2024
Countries Visited: Easter Island, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$3,296
BALCONY
$3,551
SUITE
$5,315
Save 54
From 3,296
Cruise
 (1)

15 Days (14 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Dec 2024 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Have It All Offer
INSIDE
$3,753
OCEANVIEW
$3,902
BALCONY
$5,486
SUITE
$6,545
From 3,753
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Have It All Offer
INSIDE
$4,022
OCEANVIEW
$4,160
BALCONY
$5,338
SUITE
$6,586
From 4,022
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
INSIDE
$5,330
OCEANVIEW
$6,394
BALCONY
$7,544
SUITE
$8,809
From 5,330
Cruise
 (1)

26 Days (25 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Departure: 25 February 2025
Countries Visited: Argentina, Uruguay, Brazil, French Guiana (+1 more), Barbados
Circle Club Voyage
INSIDE
-
OCEANVIEW
$11,081
BALCONY
-
SUITE
-
From 11,081
Cruise
 (3)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Departures: Nov 2024 to Feb 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,400
SUITE
$18,805
Save 1,127
From 9,400
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$18,569
SUITE
$28,614
Save 327
From 17,393
Cruise
 (1)

32 Days (31 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2024 to Nov 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+5 more), Peru, Chile, Argentina, Falkland Islands, Uruguay
Have It All Offer
INSIDE
$7,758
OCEANVIEW
$7,956
BALCONY
$10,313
SUITE
$12,619
From 7,758
Cruise
 (3)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Departures: Nov 2024 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,697
SUITE
$18,805
Save 1,120
From 9,697
Cruise
 (1)

18 Days (17 Nights) Fort Lauderdale to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2024 to Nov 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+2 more), Peru, Chile
Have It All Offer
INSIDE
$4,223
OCEANVIEW
$4,371
BALCONY
$5,549
SUITE
$7,212
From 4,223
Cruise

33 Days (32 Nights) Buenos Aires to Los Angeles
Cruise Line: Princess
Departure: 07 March 2025
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile (+5 more), Peru, Ecuador, Costa Rica, Mexico, USA
Exclusive Deal
INSIDE
$4,934
OCEANVIEW
$6,429
BALCONY
$9,003
SUITE
$10,458
From 4,934
Cruise

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Mar 2025 to Apr 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$668
OCEANVIEW
$767
BALCONY
$876
SUITE
$1,242
From 668
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Chile, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,821
Save 829
From 7,821
Cruise

14 Days (13 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2024
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 4,654
From 10,682
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 12 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$13,935
SUITE
$25,211
From 13,935
Cruise

9 Days (8 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Departure: 27 December 2024
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$3,239
OCEANVIEW
$3,388
BALCONY
$3,685
SUITE
$5,170
From 3,239
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,610
From 8,888
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Departure: 14 January 2025
Countries Visited: Argentina, Uruguay, Brazil
Cabin Upgrade Offer
INSIDE
$6,283
OCEANVIEW
$6,897
BALCONY
$7,501
SUITE
$10,214
From 6,283
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Aug 2025 to Sep 2025
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save 2,739
From 39,656
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Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Buenos Aires Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain