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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 2,036 expeditions and cruises around South America travelling with the world's leading cruise lines.
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134 Days
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367 Cruises (2,036 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 272
From (per person) 16,956
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2025 to Nov 2025
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 210
From (per person) 10,268
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Feb 2025 to Dec 2025
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save (per person) 2,075
From (per person) 5,003
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (4)

18 Days (17 Nights) Buenos Aires to Santiago
Operated By: Viking Cruises
Ship: Viking Jupiter
Departures: Nov 2025 to Feb 2027
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$10,579
SUITE
$19,791
Save (per person) 260
From (per person) 10,579
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2025 to Dec 2025
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 287
From (per person) 14,041
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Feb 2025 to Dec 2025
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 210
From (per person) 10,268
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Apr 2025 to Nov 2026
Trip Styles: Coach, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Deal
Save (per person) 256
From (per person) 14,564
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$18,569
SUITE
$28,614
Save (per person) 327
From (per person) 17,393
View Trip
23 Day Barbados To Brazil & Buenos Aires Voyage with Azamara Cruises
Cruise
 (1)

23 Days (22 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 17 January 2026
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
Circle Club Voyage
INSIDE
$11,666
OCEANVIEW
$12,428
BALCONY
$15,279
SUITE
$23,358
From (per person) 11,666
View Trip
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
Circle Club Voyage
INSIDE
$7,658
OCEANVIEW
$8,390
BALCONY
$10,638
SUITE
$13,875
From (per person) 7,658
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Feb 2025 to Mar 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$1,143
OCEANVIEW
$1,371
BALCONY
$1,727
SUITE
$2,371
From (per person) 1,143
View Trip
14 Day Argentina & the Chilean Fjords with Viking Cruises
Cruise
 (1)

14 Days (13 Nights) Buenos Aires to Santiago
Operated By: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Mar 2026 to Mar 2027
Countries Visited: Argentina, Chile
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$12,441
SUITE
$17,635
Save (per person) 304
From (per person) 12,441
View Trip
18 Day Inca & Panama Canal Discovery with Holland America
Cruise
 (2)

18 Days (17 Nights) San Antonio to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 22 March 2026
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Cayman Islands, USA
Exclusive Deal
INSIDE
$3,555
OCEANVIEW
$3,753
BALCONY
$5,100
SUITE
$7,763
From (per person) 3,555
View Trip
15 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 23 February 2027
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$3,457
OCEANVIEW
$3,853
BALCONY
$5,289
SUITE
$6,972
From (per person) 3,457
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 December 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$3,552
OCEANVIEW
$3,938
BALCONY
$5,384
SUITE
$6,869
From (per person) 3,552
View Trip
11 Day South America with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 26 December 2025
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$2,787
OCEANVIEW
$3,144
BALCONY
$3,540
SUITE
$4,629
From (per person) 2,787
View Trip
15 Day Chilean Fjords — Discovering The Heart Of Patagonia (Southbound) with HX Hurtigruten Expeditions
Cruise
 (1)

15 Days (14 Nights) Valparaiso to Buenos Aires
Ship: MS Fridtjof Nansen
Departures: Oct 2025 to Oct 2026
Countries Visited: Chile, Argentina
Wave Offer
INSIDE
-
OCEANVIEW
$9,559
BALCONY
-
SUITE
$13,583
Save (per person) 2,431
From (per person) 9,559
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Nov 2025 to Mar 2026
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$1,395
OCEANVIEW
$1,701
BALCONY
$1,949
SUITE
$2,870
From (per person) 1,395
View Trip
15 Day South America Passage with Holland America
Cruise
 (2)

15 Days (14 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Dec 2025 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$2,972
OCEANVIEW
$3,170
BALCONY
$4,417
SUITE
$6,140
From (per person) 2,972
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (1)

24 Days (23 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 January 2027
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
INSIDE
$10,145
OCEANVIEW
$11,204
BALCONY
$14,075
SUITE
$20,748
From (per person) 10,145
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2026 to Mar 2026
Countries Visited: Uruguay, Argentina, Brazil
Early Booking Offer
INSIDE
$1,744
OCEANVIEW
$2,091
BALCONY
$2,447
SUITE
$3,437
From (per person) 1,744
View Trip
18 Day Panama Canal & Inca Discovery with Holland America
Cruise
 (2)

18 Days (17 Nights) Fort Lauderdale to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departure: 17 November 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+2 more), Peru, Chile
Exclusive Deal
INSIDE
$3,207
OCEANVIEW
$3,405
BALCONY
$4,751
SUITE
$7,216
From (per person) 3,207
View Trip
11 Day South America with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 December 2025
Countries Visited: Uruguay, Argentina, Brazil
Early Booking Offer
INSIDE
$2,767
OCEANVIEW
$3,144
BALCONY
$3,540
SUITE
$4,629
From (per person) 2,767
View Trip
15 Day South America Passage with Holland America
Cruise
 (2)

15 Days (14 Nights) Buenos Aires to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departure: 08 March 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Deal
INSIDE
$3,122
OCEANVIEW
$3,320
BALCONY
$4,864
SUITE
$6,438
From (per person) 3,122
View Trip
13 Day Chilean Fjords & Scenic Shores with Viking Cruises
Cruise
 (1)

13 Days (12 Nights) Santiago to Buenos Aires
Operated By: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Oct 2025 to Nov 2026
Countries Visited: Chile, Argentina
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$12,735
SUITE
$17,635
Save (per person) 324
From (per person) 12,735
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 13 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,348
OCEANVIEW
$1,566
BALCONY
$1,793
SUITE
$2,437
From (per person) 1,348
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2026 to Mar 2026
Countries Visited: Argentina, Brazil, Uruguay
Early Booking Offer
INSIDE
$1,744
OCEANVIEW
$2,091
BALCONY
$2,269
SUITE
$3,437
From (per person) 1,744
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 20 March 2025
Countries Visited: Brazil
Save And Sail Offer
INSIDE
$786
OCEANVIEW
-
BALCONY
$1,103
SUITE
$2,013
From (per person) 786
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (4)

18 Days (17 Nights) Santiago to Buenos Aires
Operated By: Viking Cruises
Ship: Viking Jupiter
Departures: Mar 2025 to Feb 2027
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$10,775
SUITE
$19,791
Save (per person) 278
From (per person) 10,775
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 26 December 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$2,612
OCEANVIEW
$2,889
BALCONY
$3,315
SUITE
$3,988
From (per person) 2,612
View Trip
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South & Central America Cruises

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Travel Styles

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Cities

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Routes

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Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Portugal to France Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from Canada to England Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Australia to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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