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MSC Opera

MSC Opera Cruises

Choose from 245 cruise holidays onboard the MSC Opera. Compare cruises ranging from 2 days to 30 days with departures available from February 2025 through to September 2026. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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37 Cruises (245 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Italy, France, Spain, Portugal (+1 more), Sardinia
Early Booking OfferSeasational Sale
INSIDE
$1,717
OCEANVIEW
$1,905
BALCONY
$2,400
SUITE
$4,292
From (per person) 1,717
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Lisbon to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: May 2025 to Sep 2026
Countries Visited: Portugal, Spain, Sardinia, Italy (+1 more), France
Early Booking OfferSeasational Sale
INSIDE
$2,004
OCEANVIEW
$2,173
BALCONY
$2,668
SUITE
$4,292
From (per person) 2,004
View Trip
5 Day South Africa with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Feb 2025 to Mar 2026
Countries Visited: South Africa, Mozambique
Early Booking Offer
INSIDE
$661
OCEANVIEW
$750
BALCONY
$888
SUITE
$1,146
From (per person) 661
View Trip
4 Day South Africa with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Durban to Cape Town
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Mar 2025 to Mar 2026
Countries Visited: South Africa
Early Booking Offer
INSIDE
$498
OCEANVIEW
$577
BALCONY
$716
SUITE
$934
From (per person) 498
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Spain, Portugal, Sardinia, Italy (+1 more), France
Early Booking OfferSeasational Sale
INSIDE
$1,806
OCEANVIEW
$1,995
BALCONY
-
SUITE
$4,292
From (per person) 1,806
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: Spain, Sardinia, Italy, France (+1 more), Portugal
Early Booking OfferSeasational Sale
INSIDE
$1,915
OCEANVIEW
$2,103
BALCONY
-
SUITE
$4,292
From (per person) 1,915
View Trip
11 Day Mediterranean with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Opera
Departures: Apr 2025 to Sep 2026
Countries Visited: France, Spain, Portugal, Sardinia (+1 more), Italy
Early Booking OfferSeasational Sale
INSIDE
$1,777
OCEANVIEW
$1,965
BALCONY
$2,460
SUITE
$4,292
From (per person) 1,777
View Trip
29 Day MSC Grand Voyages with MSC Cruises
Cruise

29 Days (28 Nights) Bari to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 October 2025
Countries Visited: Italy, Croatia, Greece, Egypt (+6 more), Jordan, Seychelles, Madagascar, Mauritius, Reunion, South Africa
Early Booking OfferSeasational Sale
INSIDE
$3,677
OCEANVIEW
$4,389
BALCONY
-
SUITE
$9,042
From (per person) 3,677
View Trip
7 Day Canary Islands And Madeira with MSC Cruises
Cruise

7 Days (6 Nights) Santa Cruz De Tenerife to Rome
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Italy
Holiday Breaks Offer
INSIDE
$931
OCEANVIEW
$1,159
BALCONY
-
SUITE
$2,317
From (per person) 931
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: May 2025 to Oct 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Seasational Sale
INSIDE
$1,445
OCEANVIEW
$1,712
BALCONY
-
SUITE
$3,108
From (per person) 1,445
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2025 to Oct 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Seasational Sale
INSIDE
$1,435
OCEANVIEW
$1,712
BALCONY
-
SUITE
$2,950
From (per person) 1,435
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2025 to Oct 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Mutiple Deals Available
INSIDE
$1,267
OCEANVIEW
$1,534
BALCONY
-
SUITE
$3,088
From (per person) 1,267
View Trip
6 Day South Africa with MSC Cruises
Cruise

6 Days (5 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 22 December 2025
Countries Visited: South Africa, Mozambique
Early Booking Offer
INSIDE
$1,061
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 1,061
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 15 August 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Seasational Sale
INSIDE
$2,296
OCEANVIEW
-
BALCONY
-
SUITE
$3,861
From (per person) 2,296
View Trip
15 Day South Africa with MSC Cruises
Cruise

15 Days (14 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 27 December 2025
Countries Visited: South Africa, Madagascar, Mauritius, Reunion
Early Booking Offer
INSIDE
$2,883
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 2,883
View Trip
27 Day MSC Grand Voyages with MSC Cruises
Cruise

27 Days (26 Nights) Durban to Genoa
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 17 April 2026
Countries Visited: South Africa, Reunion, Mauritius, Madagascar (+5 more), Seychelles, Jordan, Egypt, Greece, Italy
Early Booking Offer
INSIDE
$3,751
OCEANVIEW
$4,394
BALCONY
-
SUITE
$8,701
From (per person) 3,751
View Trip
30 Day MSC Grand Voyages with MSC Cruises
Cruise

30 Days (29 Nights) Cape Town to Genoa
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 14 April 2026
Countries Visited: South Africa, Reunion, Mauritius, Madagascar (+5 more), Seychelles, Jordan, Egypt, Greece, Italy
Early Booking Offer
INSIDE
$4,424
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 4,424
View Trip
5 Day South Africa with MSC Cruises
Cruise

5 Days (4 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2026 to Mar 2026
Countries Visited: South Africa, Mozambique
Early Booking Offer
INSIDE
$661
OCEANVIEW
$750
BALCONY
-
SUITE
$1,146
From (per person) 661
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Madeira to Valencia
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 20 March 2025
Countries Visited: Portugal, Spain, Morocco
Save And Sail Offer
INSIDE
$1,375
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 1,375
View Trip
6 Day Cruising the Adriatic with MSC Cruises
Cruise

6 Days (5 Nights) Venice to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 06 April 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Holiday Breaks Offer
INSIDE
$913
OCEANVIEW
-
BALCONY
-
SUITE
$2,071
From (per person) 913
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 13 May 2026
Countries Visited: Italy, France, Spain, Portugal
Holiday Breaks Offer
INSIDE
$804
OCEANVIEW
$1,002
BALCONY
-
SUITE
$1,982
From (per person) 804
View Trip
27 Day MSC Grand Voyages with MSC Cruises
Cruise

27 Days (26 Nights) Venice to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 02 November 2025
Countries Visited: Italy, Croatia, Greece, Egypt (+6 more), Jordan, Seychelles, Madagascar, Mauritius, Reunion, South Africa
Early Booking OfferSeasational Sale
INSIDE
$3,373
OCEANVIEW
$4,017
BALCONY
-
SUITE
$8,323
From (per person) 3,373
View Trip
3 Day Cruising the Adriatic with MSC Cruises
Cruise

3 Days (2 Nights) Bari to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 October 2025
Countries Visited: Italy, Croatia
Holiday Breaks Offer
INSIDE
$393
OCEANVIEW
-
BALCONY
-
SUITE
$908
From (per person) 393
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Alicante
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 13 May 2026
Countries Visited: Italy, France, Spain, Portugal
Holiday Breaks Offer
INSIDE
$1,098
OCEANVIEW
$1,376
BALCONY
-
SUITE
$2,742
From (per person) 1,098
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: May 2025 to Oct 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Seasational Sale
INSIDE
$1,267
OCEANVIEW
$1,534
BALCONY
-
SUITE
$3,088
From (per person) 1,267
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Magnifica (+2 more), MSC Musica, MSC Opera
Departures: Apr 2025 to May 2026
Countries Visited: Italy, France
Holiday Breaks Offer
INSIDE
$267
OCEANVIEW
$316
BALCONY
$395
SUITE
$643
From (per person) 267
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 September 2025
Countries Visited: Italy, Croatia, Greece, Montenegro
Seasational Sale
INSIDE
$1,712
OCEANVIEW
-
BALCONY
-
SUITE
$3,356
From (per person) 1,712
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz De Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Italy, Greece
Save And Sail Offer
INSIDE
-
OCEANVIEW
$2,372
BALCONY
-
SUITE
$5,213
From (per person) 2,372
View Trip
4 Day South Africa with MSC Cruises
Cruise

4 Days (3 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2025 to Mar 2026
Countries Visited: South Africa, Mozambique
Early Booking Offer
INSIDE
$548
OCEANVIEW
$617
BALCONY
-
SUITE
$964
From (per person) 548
View Trip
8 Day Cruising the Adriatic with MSC Cruises
Cruise

8 Days (7 Nights) Venice to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: May 2025 to Jun 2025
Countries Visited: Italy, Greece, Croatia, Montenegro
Seasational SaleFlash Sale + Onboard Credit
INSIDE
$1,287
OCEANVIEW
$1,554
BALCONY
-
SUITE
-
From (per person) 1,287
View Trip
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