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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 46 departures available from eleven of the world's leading cruise lines.
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117 Days
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42 Cruises (46 Cruise Departures)
14 Day Bermuda & Portugal Transatlantic with Celebrity Cruises
Cruise
 (1)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departure: 08 March 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Endless Summer Sale
INSIDE
$2,212
OCEANVIEW
-
BALCONY
-
SUITE
-
Save (per person) 1,284
From (per person) 2,212
View Trip
16 Day Spain & Bermuda Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 26 April 2026
Countries Visited: USA, Bahamas, Bermuda, Portugal (+1 more), Spain
Exclusive DealExclusive Solo Offer
INSIDE
$2,065
OCEANVIEW
$2,426
BALCONY
$2,798
SUITE
$6,554
Save (per person) 945
From (per person) 2,065
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (7)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Operated By: Viking Cruises
Ship: Viking Mars
Departures: Mar 2025 to Jan 2027
Countries Visited: USA, Sint Maarten, Portugal, Spain
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$5,973
SUITE
$9,011
Save (per person) 128
From (per person) 5,973
View Trip
15 Day Cultural Crossing With Madeira And Gibraltar with Holland America
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Apr 2025 to Apr 2026
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,300
OCEANVIEW
$1,547
BALCONY
$1,824
SUITE
$3,181
From (per person) 1,300
View Trip
26 Day Sunlit Isles To Iberia with Oceania Cruises
Cruise
 (1)

26 Days (25 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+2 more), Morocco, Gibraltar
Exclusive Deal
INSIDE
$8,904
OCEANVIEW
$9,963
BALCONY
$13,418
SUITE
$18,675
Save (per person) 2,056
From (per person) 8,904
View Trip
15 Day Spanish Passage with Princess
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Mar 2025 to Mar 2026
Countries Visited: USA, Spain
Exclusive Deal
INSIDE
$1,193
OCEANVIEW
$1,290
BALCONY
$1,555
SUITE
$2,867
From (per person) 1,193
View Trip
15 Day Exotic Atlantic Crossing with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 22 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive DealFlash Sale + Bonus Onboard Credit
INSIDE
$3,485
OCEANVIEW
$3,804
BALCONY
-
SUITE
-
Save (per person) 3,525
From (per person) 3,485
View Trip
16 Day Transatlantic Repositioning Cruise From Miami to Barcelona with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 14 April 2026
Countries Visited: USA, Portugal, Spain, Italy (+1 more), France
NCL's More at Sea
INSIDE
$4,674
OCEANVIEW
$4,903
BALCONY
$5,439
SUITE
$7,137
From (per person) 4,674
View Trip
25 Day Transatlantic Tranquility with Oceania Cruises
Cruise
 (3)

25 Days (24 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 April 2025
Countries Visited: USA, Saint Barthelemy, Virgin Islands, Antigua and Barbuda (+4 more), Saint Kitts and Nevis, Bermuda, Portugal, Spain
Exclusive Deal
INSIDE
$9,055
OCEANVIEW
$9,649
BALCONY
-
SUITE
-
Save (per person) 2,065
From (per person) 9,055
View Trip
17 Day Transatlantic Repositioning Cruise From New York to Barcelona with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 26 September 2026
Countries Visited: USA, Canada, Portugal, Spain (+1 more), Gibraltar
NCL's More at Sea
INSIDE
$4,431
OCEANVIEW
$5,027
BALCONY
$5,700
SUITE
$6,404
From (per person) 4,431
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Orlando to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 18 April 2026
Countries Visited: USA, Saint Martin, Portugal, Spain (+2 more), France, Italy
Early Booking Offer
INSIDE
$2,791
OCEANVIEW
$3,355
BALCONY
$3,603
SUITE
-
From (per person) 2,791
View Trip
84 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

84 Days (83 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 July 2025
Countries Visited: USA, Canada, Greenland, Iceland (+19 more), Faroe Islands, Scotland, Northern Ireland, England, Ireland, Wales, France, Belgium, Holland, Denmark, Germany, Poland, Lithuania, Latvia, Sweden, Norway, Guernsey, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$105,598
SUITE
$108,994
Save (per person) 29,122
From (per person) 105,598
View Trip
16 Day Transatlantic Repositioning Cruise From New York to Barcelona with Norwegian Cruise Line
Cruise

16 Days (15 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 09 April 2026
Countries Visited: USA, Canada, Portugal, Spain (+1 more), France
NCL's More at Sea
INSIDE
$4,187
OCEANVIEW
$4,417
BALCONY
$6,053
SUITE
$6,328
From (per person) 4,187
View Trip
25 Day Caribbean And Antilles with MSC Cruises
Cruise

25 Days (24 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 March 2026
Countries Visited: USA, Jamaica, Aruba, Colombia (+5 more), Panama, Honduras, Bahamas, Virgin Islands, Spain
Early Booking Drinks Package
INSIDE
$5,586
OCEANVIEW
$6,299
BALCONY
$6,566
SUITE
$9,873
From (per person) 5,586
View Trip
17 Day A Grand Journey Bridging America, Azore Isles and Catalonia with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 02 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Unique Oceans Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$20,305
From (per person) 20,305
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 26 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Endless Summer Sale
INSIDE
$3,489
OCEANVIEW
$3,861
BALCONY
$4,084
SUITE
$10,037
Save (per person) 2,015
From (per person) 3,489
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Orlando to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 11 April 2026
Countries Visited: USA, Bahamas, Dominican Republic, Saint Martin (+2 more), Portugal, Spain
Early Booking Offer
INSIDE
$2,943
OCEANVIEW
$3,527
BALCONY
$4,062
SUITE
$6,814
From (per person) 2,943
View Trip
16 Day Transatlantic Repositioning Cruise From Miami to Barcelona with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 11 April 2026
Countries Visited: USA, Portugal, Spain
NCL's More at Sea
INSIDE
$3,972
OCEANVIEW
$4,233
BALCONY
$5,456
SUITE
$5,915
From (per person) 3,972
View Trip
17 Day A Grand Journey From Levely Latin Charm & Tropical Delights To Modernist Marvels with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 09 March 2026
Countries Visited: USA, Puerto Rico, Saint Martin, Spain (+1 more), Gibraltar
Unique Oceans OfferExplora Early Booking Benefit
INSIDE
-
OCEANVIEW
-
BALCONY
$11,038
SUITE
$12,697
From (per person) 11,038
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 April 2026
Countries Visited: USA, Virgin Islands, Spain
Early Booking Offer
INSIDE
$2,283
OCEANVIEW
$2,570
BALCONY
$3,055
SUITE
$6,763
From (per person) 2,283
View Trip
13 Day Spain & Azores Transatlantic with Royal Caribbean
Cruise

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 30 April 2025
Countries Visited: USA, Portugal, Spain
Exclusive DealExclusive Solo Offer
INSIDE
-
OCEANVIEW
$2,604
BALCONY
$3,240
SUITE
$3,656
Save (per person) 1,308
From (per person) 2,604
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Gibraltar (+1 more), Spain
Mutiple Deals Available
INSIDE
$4,164
OCEANVIEW
$5,237
BALCONY
$5,701
SUITE
$8,443
Save (per person) 2,246
From (per person) 4,164
View Trip
16 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

16 Days (15 Nights) New York to Barcelona
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 15 March 2026
Countries Visited: USA, Portugal, Spain, Gibraltar
Exclusive DealExclusive Solo Offer
INSIDE
$2,140
OCEANVIEW
$2,509
BALCONY
$2,514
SUITE
$6,079
Save (per person) 1,055
From (per person) 2,140
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 18 April 2026
Countries Visited: USA, Saint Martin, Portugal, Spain
Early Booking Offer
INSIDE
$1,949
OCEANVIEW
$2,336
BALCONY
$2,504
SUITE
$7,989
From (per person) 1,949
View Trip
29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+3 more), Morocco, Italy, France
Upgrade Your HorizonExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$26,634
SUITE
$28,109
Save (per person) 11,236
From (per person) 26,634
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) New York to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 19 April 2026
Countries Visited: USA, Canada, Portugal, Spain (+2 more), Gibraltar, France
Early Booking Offer
INSIDE
$2,372
OCEANVIEW
$2,807
BALCONY
$3,045
SUITE
$6,837
From (per person) 2,372
View Trip
15 Day Royal Bermuda & Regal Spain with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 19 March 2025
Countries Visited: USA, Bahamas, Bermuda, Portugal (+1 more), Spain
Upgrade Your HorizonExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,400
SUITE
$12,429
Save (per person) 7,050
From (per person) 11,400
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 23 April 2026
Countries Visited: USA, Portugal, Spain
Exclusive DealExclusive Solo Offer
INSIDE
$1,584
OCEANVIEW
$1,705
BALCONY
$2,367
SUITE
$3,809
Save (per person) 842
From (per person) 1,584
View Trip
15 Day New York Transatlantic to Spain with Virgin Voyages
Cruise

15 Days (14 Nights) New York to Barcelona
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 25 April 2026
Countries Visited: USA, Portugal, Morocco, Spain
Up To USD $300 Bar Tab
INSIDE
$1,575
OCEANVIEW
$1,711
BALCONY
$2,256
SUITE
$13,193
From (per person) 1,575
View Trip
16 Day Miami to Casablanca & Barcelona with Virgin Voyages
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 03 May 2025
Countries Visited: USA, Spain, Morocco
Up To USD $300 Bar Tab
INSIDE
$2,414
OCEANVIEW
$2,902
BALCONY
$3,292
SUITE
$13,401
From (per person) 2,414
View Trip
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